The antiretroviral drugs dolutegravir and emtricitabine/tenofovir alafenamide fumarate (DTG+FTC/TAF) may comprise the safest and most effective HIV treatment regimen currently available during pregnancy, researchers announced today.

Are Arvs safe during pregnancy?

Are antiretrovirals safe for my baby? Research suggests that anti-HIV drugs are safe to use in pregnancy. There may be a slightly increased risk of giving birth prematurely or having a low birth-weight baby. However, other research suggests antiretrovirals dont contribute to premature births.

Which Nnrti is safe for use in pregnancy?

In pregnant women in need of ART for their own health the preferred first-line ART regimen should include an AZT + 3TC backbone in combination with an NNRTI: AZT + 3TC + NVP or AZT + 3TC + EFV. Alternative recommended regimens are TDF + 3TC (or FTC) + EFV and TDF + 3TC (or FTC) + NVP.

In which trimester of pregnancy is antiretroviral therapy safe?

Initiate treatment as soon as possible, including in the first trimester. The preferred initial regimen in pregnancy is a backbone of dual nucleoside analogue reverse transcriptase inhibitors (NRTI) with either ritonavir-boosted protease inhibitor (PI) or an integrase Inhibitor.

Does CD4 count drop during pregnancy?

The CD4 drop in pregnancy can vary but it is usually about 50 cells. It is not a real reduction in CD4 cells but the same amount in a larger amount of blood (the amount of blood increases when you are pregnant). The drop is only temporary.

What medicine should you avoid when pregnant?

What medicines should you avoid during pregnancy?Bismuth subsalicylate (such as Pepto-Bismol).Phenylephrine or pseudoephedrine, which are decongestants. Cough and cold medicines that contain guaifenesin. Pain medicines like aspirin and ibuprofen (such as Advil and Motrin) and naproxen (such as Aleve).